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Beginning of June 2017, the German Federal Institute for Occupational Safety and Health (BAuA) has published the final report for the project "Methodology for the Identification of Granular Biopersistent Particles (GBP) at Workplaces".
The final report states that the category includes respirable granular biopersistent particles without known significant specific toxicity. This category comprises various materials such as minerals, metals, metal oxides, or polymers that show a negligible solubility in lung fluids.
The project consisted of the following three modules:
- Module 1: In vivo study - Analysis of the bronchoalveolar lavage fluid (BALF) following intratracheal instillation
- Module 1: In vivo study - Chemical analysis of the lung burdens
- Module 2: In vitro assays
- Module 3: Acellular solubility of test materials
- Read the complete article (baua.de, June 2017) online via https://www.baua.de/EN/Service/Publications/Report/F2336.html
Original Publication
Creutzenberg O., Koch W., Hansen T., Knebel J., Schuchardt S. (2017). Methodology for the Identification of Granular Biopersistent Particles (GBP) at Workplaces. 1. edition. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin 2017. pages 102, Project number: F 2336,. DOI: 10.21934/baua:bericht20170419 (PDF, 2.8 MB).
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Spotlight Research
Nano-safety - topic of the future
In October we would like to present the special issue "Future Nanosafety" published in "Chemical Research in Toxicology".
In 17 articles operation procedures for future test methods, alternatives for animal testing, safe-by-design processes and detection methods of nanoparticles are presented.