NanoToxClass Project Logo

On 14 and 15 January 2016, international experts representing academia, government authorities and industry convened at the German Federal Institute for Risk Assessment (BfR) for the joint launch event to the international research project NanoToxClass. Sponsored for three years as part of the EU funding scheme ERA-NET SIINN, the project is co-sponsored by Germany, Belgium, Israel, Portugal and Romania with total funds amounting to just under EUR 1.6 million.

At present, each nanomaterial is subjected to its own experimental testing which is both time-consuming and expensive. The aim of the NanoToxClass project is therefore to develop classification methods for nanomaterials based on their hazard potential for humans. In particular, nanomaterials of wide industrial use will be taken into account. "The results of the project are highly relevant for regulatory practice, since classification will make the assessment of their health effects much easier", says BfR President Professor Dr. Dr. Andreas Hensel.


One important focus of the NanoToxClass project is the systematic generation of new data on the mode of action of nanomaterials by means of modern technology used in systems biology. These data are then used in combination with established toxicological endpoints. The project will furthermore incorporate transcriptome, metabolome and proteome analysis based on data derived from in vitro and in vivo experiments. Thus, the approach chosen allows for considering the mode of action of nanomaterials in the development of hazard categories. In addition, by correlating in vitro and in vivo data, this approach facilitates the development of new testing strategies and selective refinement of existing in vitro tests......



Find out more about the NanoToxClass Project in our Projects-Section!!!!




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