BAuA report

Beginning of June 2017, the German Federal Institute for Occupational Safety and Health (BAuA) has published the final report for the project "Methodology for the Identification of Granular Biopersistent Particles (GBP) at Workplaces".


The final report states that the category includes respirable granular biopersistent particles without known significant specific toxicity. This category comprises various materials such as minerals, metals, metal oxides, or polymers that show a negligible solubility in lung fluids.

The project consisted of the following three modules:

  • Module 1: In vivo study - Analysis of the bronchoalveolar lavage fluid (BALF) following intratracheal instillation
  • Module 1: In vivo study - Chemical analysis of the lung burdens
  • Module 2: In vitro assays
  • Module 3: Acellular solubility of test materials


  • Read the complete article (, June 2017) online via


Original Publication

Creutzenberg O., Koch W., Hansen T., Knebel J., Schuchardt S. (2017). Methodology for the Identification of Granular Biopersistent Particles (GBP) at Workplaces. 1. edition. Dortmund: Bundesanstalt für Arbeitsschutz und Arbeitsmedizin 2017. pages 102, Project number: F 2336,. DOI: 10.21934/baua:bericht20170419 (PDF, 2.8 MB).



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