OECD report 2017 alternative testing strategies

The Organisation for Economic Co-operation and Development (OECD) has published a new report, which describes the state of the science in alternative testing strategies in risk assessment of manufactured nanomaterials.


The report, which is being published under the responsibility of the Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology, includes considerations on how alternative testing strategies could be used in a risk analysis context to inform human health, ecosystem health, and exposure data needs for manufactured nanomaterials in the near term and longer term, as well as identifying research needs to support the development of these strategies in the near future. One conclusion was that alternative testing strategies are currently being used for screening, and that, in the near term, alternative testing strategies could be developed for use in read-across or categorisation decision making within certain regulatory frameworks.


Experts recognised that leadership is required from within the scientific community to address basic challenges, such as standardisation of materials, techniques and reporting, designing experiments relevant to realistic outcomes, as well as coordination and sharing of large-scale collaborations and data. It is expected that the conclusions from this document can contribute to the development and implementation of relevant alternative testing strategies for nanomaterials' testing that will expedite the ability to identify high-risk MNs, and lead to more rapid, cost-effective, and reliable nanomaterial safety testing for specific risk management decision context...






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