Cerium dioxide - Behaviour

If cerium dioxide is delivered directly into the blood stream via intravenous injection adverse effects could be observed only at very high concentrations.

Cerium dioxide nanoparticles will be taken up by human lung cells even at low concentrations via a vesicle-dependent process.

Animal studies with rats have shown that cerium dioxide nanoparticles deposit in the lung after inhalation but do not reach the brain. Typically, the blood-brain-barrier is impermeable to nanoparticles which only pass this barrier when precisely targeted with specific surface coatings.

The environmental behaviour of cerium dioxide nanoparticles (CeO2) is not well known. However, they are subject to various transport and transformation processes, which significantly influence the nanoparticles' behaviour in the respective environmental compartment water, soil and air.


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